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Psoriasis Treatments: Propionate Cream, Corticosteroids And Inflammatory Skin Disorders
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Published: July 30, 2007
Anyone who has had to endure psoriasis knows how painful it can be. It not only feels tremendously uncomfortable, but it can be quite an embarrassment because as an inflammatory skin disorder, it is visible to others. Psoriasis can negatively affect the sufferer's physical well-being and self-esteem.
Anyone who believes he or she has psoriasis should carefully examine his or her symptoms to be certain of it. Usually, the skin will thicken, turn red and form into scaly patches called plaques. Plaques can manifest anywhere but most often show up on the knees, elbows and scalp. This plaque psoriasis is the most common form of the disease, afflicting about eighty percent of psoriasis sufferers. The four other types are inverse psoriasis, guttate psoriasis, pustular psoriasis and erythrodermic psoriasis.
Around ten to thirty percent of psoriasis sufferers also get psoriatic arthritis, in which the joints as well as the skin are inflamed. This inflammation in the bodily tissues comes from flawed reactions and messages within a person's immune system. The skin cells are renewed far too quickly, causing a pile-up on the skin's surface. Therefore, no one should fear that psoriasis is contagious, such as poison ivy.
Fortunately, modern medicine has been able to find remedies for inflammatory skin disorders such as psoriasis. Because it is a chronic and often a severe condition, many of these psoriasis treatments are very potent and available only by prescription. Propionate Cream is one of these.
Propionate Cream is made from clobetasol propionate, a synthetic corticosteroid intended for topical application. Corticosteroid has an anti-inflammatory and anti-itching effect on psoriatic skin. It comes under different brand names including Temovate, Clobex and Cormax. Propionate Cream is one of the strongest Psoriasis treatments on the market, for the most virulent and stubborn cases of these inflammatory skin disorders. But Propionate Cream has been established it has a potentially damaging effect on the endocrine system - specifically the hypothalamic-pituitary-adrenal (HPA) axis. So Propionate Cream must not be used for any longer than two weeks or in any amount greater than 50 grams at a time.
Use can possibly extend to four weeks if used to treat only 5 to 10 percent of the body's total skin surface at a time. However, if one is going to use it for longer than two weeks, the benefits of the Propionate Cream must be considered versus the possible damage to the HPA axis. Even just two grams of Propionate Cream per day can have an effect, so one must be especially careful. Patients using Propionate Cream must be sure to follow their physicians' directions exactly. Propionate Cream must never be used on children under the age of 12, and though studies have not yet actually proven it causes birth defects in humans, pregnant women should not use Propionate Cream unless the benefits outweigh the risks.
Also, because of the harshness of the chemicals in Propionate Cream, it is advisable for a patient to first test a small area of skin to make sure that no extreme irritation will develop later.
Propionate Cream needs to be subjected to further clinical study. In the meantime, the proverbial lesson applies - a little bit goes a long way. Propionate Cream can successfully treat psoriasis, but it can harm just as much as it can heal. All patients, no matter what age or gender, should think carefully before considering it as a treatment. Physicians must do their utmost to give their patients clear and concise instructions on safe Propionate Cream usage.
Sources:
Temovate (Clobetasol Propionate) Cream, 0.05%. PharmaDerm. 2005. PharmaDerm. 16 July 2007.
http://www.pharmaderm.com/physician_info/temovat e/temovate_cream.html
Clobetasol Prpionate (clobetisol propionate) Cream. Daily Med. Aug. 2006. U.S. National Library of Medicine. 16 July 2007. http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm? id=1691
"What Is Psoriasis?" PsoriasisNet. 2007. American Academy of Dermatology. 16 July 2007.
http://www.skincarephysicians.com/psoriasisnet/w hatis.html
"Topical Steroids - Potencies of Topical Steroids." National Psoriasis Foundation. 2007. National Psoriasis Foundation USA. 16 July 2007. http://www.psoriasis.org/treatment/psoriasis/stero ids/potency.php
Anyone who believes he or she has psoriasis should carefully examine his or her symptoms to be certain of it. Usually, the skin will thicken, turn red and form into scaly patches called plaques. Plaques can manifest anywhere but most often show up on the knees, elbows and scalp. This plaque psoriasis is the most common form of the disease, afflicting about eighty percent of psoriasis sufferers. The four other types are inverse psoriasis, guttate psoriasis, pustular psoriasis and erythrodermic psoriasis.
Around ten to thirty percent of psoriasis sufferers also get psoriatic arthritis, in which the joints as well as the skin are inflamed. This inflammation in the bodily tissues comes from flawed reactions and messages within a person's immune system. The skin cells are renewed far too quickly, causing a pile-up on the skin's surface. Therefore, no one should fear that psoriasis is contagious, such as poison ivy.
Fortunately, modern medicine has been able to find remedies for inflammatory skin disorders such as psoriasis. Because it is a chronic and often a severe condition, many of these psoriasis treatments are very potent and available only by prescription. Propionate Cream is one of these.
Propionate Cream is made from clobetasol propionate, a synthetic corticosteroid intended for topical application. Corticosteroid has an anti-inflammatory and anti-itching effect on psoriatic skin. It comes under different brand names including Temovate, Clobex and Cormax. Propionate Cream is one of the strongest Psoriasis treatments on the market, for the most virulent and stubborn cases of these inflammatory skin disorders. But Propionate Cream has been established it has a potentially damaging effect on the endocrine system - specifically the hypothalamic-pituitary-adrenal (HPA) axis. So Propionate Cream must not be used for any longer than two weeks or in any amount greater than 50 grams at a time.
Use can possibly extend to four weeks if used to treat only 5 to 10 percent of the body's total skin surface at a time. However, if one is going to use it for longer than two weeks, the benefits of the Propionate Cream must be considered versus the possible damage to the HPA axis. Even just two grams of Propionate Cream per day can have an effect, so one must be especially careful. Patients using Propionate Cream must be sure to follow their physicians' directions exactly. Propionate Cream must never be used on children under the age of 12, and though studies have not yet actually proven it causes birth defects in humans, pregnant women should not use Propionate Cream unless the benefits outweigh the risks.
Also, because of the harshness of the chemicals in Propionate Cream, it is advisable for a patient to first test a small area of skin to make sure that no extreme irritation will develop later.
Propionate Cream needs to be subjected to further clinical study. In the meantime, the proverbial lesson applies - a little bit goes a long way. Propionate Cream can successfully treat psoriasis, but it can harm just as much as it can heal. All patients, no matter what age or gender, should think carefully before considering it as a treatment. Physicians must do their utmost to give their patients clear and concise instructions on safe Propionate Cream usage.
Sources:
Temovate (Clobetasol Propionate) Cream, 0.05%. PharmaDerm. 2005. PharmaDerm. 16 July 2007.
http://www.pharmaderm.com/physician_info/temovat e/temovate_cream.html
Clobetasol Prpionate (clobetisol propionate) Cream. Daily Med. Aug. 2006. U.S. National Library of Medicine. 16 July 2007. http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm? id=1691
"What Is Psoriasis?" PsoriasisNet. 2007. American Academy of Dermatology. 16 July 2007.
http://www.skincarephysicians.com/psoriasisnet/w hatis.html
"Topical Steroids - Potencies of Topical Steroids." National Psoriasis Foundation. 2007. National Psoriasis Foundation USA. 16 July 2007. http://www.psoriasis.org/treatment/psoriasis/stero ids/potency.php
